
Capsules
Cadmizorb-Plus Capsule
Calcium carbonate, calcitriol, vitamin K2-7, methylcobalamin, magnesium, boron and zinc soft-gel capsules
Cadmizorb-Plus is a registered product of Ramnova Healthcare Private Limited.
Cadmizorb-Plus Capsule composition
Product composition
| Ingredient | Strength |
|---|---|
| Calcium carbonate | 200 mg |
| Calcitriol | 0.25 mcg |
| Vitamin K2-7 | 45 mcg |
| Methylcobalamin | 750 mcg |
| Magnesium | 20 mg |
| Boron | 1.5 mg |
| Zinc | 7.5 mg |
About Cadmizorb-Plus Capsule
CADMIZORB-PLUS soft-gel capsules combine calcium carbonate 200 mg with calcitriol 0.25 mcg, the active form of vitamin D, plus vitamin K2-7, methylcobalamin (vitamin B12), magnesium, boron and zinc. It is used to treat calcium deficiency and to support bone health, including in people with osteoporosis.
Take it at the same time each day, exactly as your doctor prescribes, and do not take more than advised. Because calcitriol is a strong form of vitamin D, your doctor may check your blood calcium during treatment. Tell your doctor about any other medicines and supplements you take, especially other vitamin D or calcium products.
Therapy category: Bone health and nutrition.
Uses of Cadmizorb-Plus Capsule
- Calcium deficiency
- Supporting bone health in osteoporosis and low bone density
Benefits of Cadmizorb-Plus Capsule
Calcium deficiency
Calcium is needed for strong bones and teeth, and for normal nerve, muscle and heart function. Calcium carbonate tops up the calcium in your diet, and calcitriol, the active form of vitamin D, helps your gut absorb it. Magnesium and zinc also support normal bone metabolism.
Bone health in osteoporosis
In osteoporosis, bones become thinner and more likely to break. Calcium with active vitamin D helps maintain bone mineral density, while vitamin K2-7 activates proteins that help bind calcium into bone. Your doctor may prescribe it alongside other osteoporosis treatment.
Side effects of Cadmizorb-Plus Capsule
Most side effects are mild and settle as your body adjusts. Tell your doctor if they continue or worry you.
- Constipation, wind or bloating
- Nausea or stomach upset
- Headache
- Loss of appetite
- Rash or itching
- High blood calcium with long-term or excessive use (see warnings)
How to take Cadmizorb-Plus Capsule
Take this medicine in the dose and for the length of time your doctor advises. Swallow the capsule whole with water; do not chew or break it. Taking it with or after a meal can help calcium absorption and reduce stomach upset.
How Cadmizorb-Plus Capsule works
Calcium carbonate supplies calcium, the main mineral in bones and teeth. Calcitriol, the active form of vitamin D, increases the amount of calcium the gut absorbs. Vitamin K2-7 activates proteins that help bind calcium into bone, while magnesium, zinc and boron support normal bone metabolism. Methylcobalamin is an active form of vitamin B12, needed for healthy nerves and red blood cells.
Safety advice for Cadmizorb-Plus Capsule
- Consult your doctor
Alcohol
It is not known whether alcohol interacts with this medicine. Heavy drinking also weakens bones, so limit alcohol and ask your doctor.
- Consult your doctor
Pregnancy
Use only if your doctor advises it. Calcitriol needs careful supervision during pregnancy.
- Use with caution
Breastfeeding
Calcitriol passes into breast milk. Your doctor may monitor calcium levels in you and your baby.
- Safe
Driving
Not expected to affect your ability to drive.
- Use with caution
Kidney
Tell your doctor if you have kidney disease, are on dialysis or have had kidney stones. The dose may need adjusting and your calcium checking.
- Use with caution
Liver
Tell your doctor if you have severe liver disease, as the dose may need adjusting.
Quick tips
- Take it at the same time each day, preferably after a meal.
- Do not take other vitamin D or calcium supplements unless your doctor advises it.
- Keep at least 2 hours between this capsule and iron tablets, thyroid medicine, or antibiotics such as ciprofloxacin or doxycycline.
- Include calcium-rich foods such as milk, curd, paneer, ragi and green leafy vegetables.
- Drink plenty of water, and tell your doctor if you have had kidney stones.
- See your doctor if you notice excessive thirst, frequent urination, nausea, constipation, confusion or unusual tiredness, which can be signs of high calcium.
Warnings and interactions
Safety details must be checked against the current pack insert and advice from a qualified healthcare professional.
Warnings
- Calcitriol can raise blood calcium too high (hypercalcaemia). Your doctor may check your calcium and kidney function regularly, especially when starting treatment or changing the dose.
- Avoid other vitamin D products, including high-dose vitamin D supplements, unless your doctor advises them.
- The risk of high calcium is greater if you are immobile for long periods, for example after surgery.
- If you are on long-term kidney dialysis, your doctor will decide whether this product is suitable, because it contains magnesium as well as calcitriol.
- Tell your doctor if you have kidney disease, kidney stones or a heart rhythm problem.
Contraindications
- High blood calcium (hypercalcaemia) or a condition that causes it
- Vitamin D toxicity
- Calcium deposits in body tissues (metastatic calcification)
- Allergy to any ingredient of the capsule
Important interactions
- Thiazide water tablets, such as hydrochlorothiazide, can increase the risk of high calcium.
- High calcium can increase the risk of heart rhythm problems in people taking digoxin.
- Vitamin K2-7 can reduce the effect of blood thinners such as warfarin or acenocoumarol, so your doctor may need to check your INR.
- Calcium, magnesium and zinc reduce the absorption of some antibiotics (tetracyclines and ciprofloxacin), thyroid medicine, iron and bisphosphonates. Take them at least 2 hours apart, or as your doctor advises.
- Cholestyramine and sevelamer reduce calcitriol absorption, and corticosteroids can reduce its effect.
Frequently asked questions about Cadmizorb-Plus Capsule
- Cadmizorb-Plus Capsule is used for: calcium deficiency; and supporting bone health in osteoporosis and low bone density.
- Common side effects of Cadmizorb-Plus Capsule include: constipation, wind or bloating; nausea or stomach upset; headache; loss of appetite; rash or itching; and high blood calcium with long-term or excessive use (see warnings). Tell your doctor if they continue or worry you.
- Take this medicine in the dose and for the length of time your doctor advises. Swallow the capsule whole with water; do not chew or break it. Taking it with or after a meal can help calcium absorption and reduce stomach upset.
- Do not take Cadmizorb-Plus Capsule in the following cases: high blood calcium (hypercalcaemia) or a condition that causes it; vitamin D toxicity; calcium deposits in body tissues (metastatic calcification); and allergy to any ingredient of the capsule.
- It is not known whether alcohol interacts with this medicine. Heavy drinking also weakens bones, so limit alcohol and ask your doctor.
- Use only if your doctor advises it. Calcitriol needs careful supervision during pregnancy.
- Not expected to affect your ability to drive.
- Cadmizorb-Plus is a registered product of Ramnova Healthcare Private Limited, Silvassa, India, and is marketed by Ramnova Healthcare.
- Cadmizorb-Plus Capsule contains calcium carbonate 200 mg, calcitriol 0.25 mcg, vitamin K2-7 45 mcg, methylcobalamin 750 mcg, magnesium 20 mg and 2 other vitamins, minerals and nutrients in each capsule; see the full composition table above.
What is Cadmizorb-Plus Capsule used for?
What are the side effects of Cadmizorb-Plus Capsule?
How should I take Cadmizorb-Plus Capsule?
Who should not take Cadmizorb-Plus Capsule?
Can I drink alcohol with Cadmizorb-Plus Capsule?
Is Cadmizorb-Plus Capsule safe in pregnancy?
Can I drive after taking Cadmizorb-Plus Capsule?
Who markets Cadmizorb-Plus Capsule?
What is the composition of Cadmizorb-Plus Capsule?
More information
Marketed by Ramnova Healthcare Private Limited, Silvassa, India.
For dosage, pack sizes or prescribing information, refer to the current pack insert or contact Ramnova Healthcare. Catalogue information updated 2026-10-01.
- electronic medicines compendium (emc): Calcitriol 0.25 microgram capsules: Summary of Product Characteristics (United Kingdom, accessed 2026-10-01)



