Syrups
Ursoram-125 Suspension
Ursodeoxycholic acid 125 mg/5 ml oral suspension
Ursoram-125 is a registered product of Ramnova Healthcare Private Limited.
Ursoram-125 Suspension composition
Each 5 ml contains
| Ingredient | Strength |
|---|---|
| Ursodeoxycholic acid | 125 mg |
Also in the Ursoram range
About Ursoram-125 Suspension
URSORAM-125 suspension contains 125 mg of ursodeoxycholic acid, a bile acid, in every 5 ml of a flavoured liquid that is easier to take for children and for people who have difficulty swallowing tablets. It is used to dissolve cholesterol gallstones and to treat certain long-term liver conditions, including primary biliary cholangitis and liver problems linked to cystic fibrosis in children.
Shake the bottle well and give the dose your doctor prescribes, which is usually based on body weight, using the measuring cup provided, preferably after meals. The most common side effect is soft stools or diarrhoea. It is a prescription medicine and should be used under a doctor's supervision.
Therapy category: Hepatobiliary care.
Uses of Ursoram-125 Suspension
- Dissolving cholesterol gallstones in people whose gallbladder is still working
- Primary biliary cholangitis (PBC)
- Liver disease associated with cystic fibrosis in children
Benefits of Ursoram-125 Suspension
Cholesterol gallstones
Ursodeoxycholic acid lowers the amount of cholesterol in bile, which allows small cholesterol stones in a working gallbladder to dissolve slowly. This can take several months, so give it regularly for as long as the doctor advises. The doctor may arrange scans to check progress.
Primary biliary cholangitis (PBC)
In PBC, the small bile ducts inside the liver are gradually damaged and bile builds up. Ursodeoxycholic acid improves bile flow and protects liver cells from harmful bile acids, which can slow the disease and improve liver test results. It is usually taken long term.
Liver disease associated with cystic fibrosis
In cystic fibrosis, thick bile can block the small bile ducts and damage the liver. Ursodeoxycholic acid helps bile flow more easily and protects liver cells. In the UK the liquid form is approved for this use in children from 1 month to 18 years.
Side effects of Ursoram-125 Suspension
Most side effects are mild and settle as your body adjusts. Tell your doctor if they continue or worry you.
- Soft stools or diarrhoea (the most common side effect)
- Nausea or vomiting
- Abdominal pain
- Itching or hives
How to take Ursoram-125 Suspension
Shake the bottle well before each dose. Give the dose your doctor prescribes, usually worked out from body weight, using the measuring cup or syringe provided rather than a kitchen spoon, preferably after meals. Keep the bottle tightly closed in a cool, dry, dark place, away from light and moisture.
How Ursoram-125 Suspension works
Ursodeoxycholic acid is a bile acid that occurs naturally in small amounts in the body. It reduces the cholesterol that the liver releases into bile, which helps cholesterol gallstones dissolve. It also replaces more harmful bile acids, improves bile flow and protects liver cells from damage.
Safety advice for Ursoram-125 Suspension
- Consult your doctor
Alcohol
It is not known whether alcohol is safe with this medicine. Adults should limit alcohol and ask their doctor.
- Use with caution
Pregnancy
Not recommended during pregnancy unless your doctor considers it clearly necessary. Women who could become pregnant should use non-hormonal contraception.
- Safe if prescribed
Breastfeeding
Only very small amounts pass into breast milk, and no effects on the baby are expected. Use as your doctor advises.
- Safe
Driving
Not expected to affect the ability to drive.
- Consult your doctor
Kidney
There is limited information in kidney disease. Tell the doctor about any kidney problem.
- Safe if prescribed
Liver
Used to treat certain liver conditions. Use only as prescribed, with regular liver tests.
Quick tips
- Shake well and measure each dose with the cup or syringe provided, not a kitchen spoon.
- Give it after meals, at the same times each day.
- Avoid fatty, oily meals.
- If diarrhoea develops, give plenty of fluids and tell the doctor if it continues.
- Regular liver blood tests are usually needed during treatment.
- Get medical help quickly for worsening jaundice, severe itching, dark urine or ongoing abdominal pain.
Warnings and interactions
Safety details must be checked against the current pack insert and advice from a qualified healthcare professional.
Warnings
- Treatment should be supervised by a doctor. Liver function is usually checked every 4 weeks for the first 3 months, then every 3 months.
- If diarrhoea continues, the dose may need to be reduced or treatment stopped.
- Women taking it to dissolve gallstones should use non-hormonal contraception.
- It contains the colour sunset yellow (E110), which can cause allergic reactions in some people.
Contraindications
- Acute inflammation of the gallbladder or bile ducts
- Blockage of the bile ducts
- Frequent episodes of biliary colic (severe pain in the upper abdomen)
- Calcified gallstones, or a gallbladder that does not contract properly
- In children with biliary atresia: an unsuccessful operation to restore bile flow
- Allergy to ursodeoxycholic acid or any other ingredient
Important interactions
- Antacids containing aluminium, cholestyramine and colestipol reduce absorption. Give them at least 2 hours apart.
- It can affect the absorption of ciclosporin and ciprofloxacin, and may reduce the effect of nitrendipine and dapsone.
- Medicines containing oestrogen, including hormonal contraceptives, and clofibrate can raise cholesterol in bile and may reduce its effect on gallstones.
Frequently asked questions about Ursoram-125 Suspension
- Ursoram-125 Suspension is used for: dissolving cholesterol gallstones in people whose gallbladder is still working; primary biliary cholangitis (PBC); and liver disease associated with cystic fibrosis in children.
- Common side effects of Ursoram-125 Suspension include: soft stools or diarrhoea (the most common side effect); nausea or vomiting; abdominal pain; and itching or hives. Tell your doctor if they continue or worry you.
- Shake the bottle well before each dose. Give the dose your doctor prescribes, usually worked out from body weight, using the measuring cup or syringe provided rather than a kitchen spoon, preferably after meals. Keep the bottle tightly closed in a cool, dry, dark place, away from light and moisture.
- Do not take Ursoram-125 Suspension in the following cases: acute inflammation of the gallbladder or bile ducts; blockage of the bile ducts; frequent episodes of biliary colic (severe pain in the upper abdomen); calcified gallstones, or a gallbladder that does not contract properly; in children with biliary atresia: an unsuccessful operation to restore bile flow; and allergy to ursodeoxycholic acid or any other ingredient.
- It is not known whether alcohol is safe with this medicine. Adults should limit alcohol and ask their doctor.
- Not recommended during pregnancy unless your doctor considers it clearly necessary. Women who could become pregnant should use non-hormonal contraception.
- Not expected to affect the ability to drive.
- Ursoram-125 is a registered product of Ramnova Healthcare Private Limited, Silvassa, India, and is marketed by Ramnova Healthcare.
- Ursoram-125 Suspension contains ursodeoxycholic acid 125 mg in each 5 ml.
What is Ursoram-125 Suspension used for?
What are the side effects of Ursoram-125 Suspension?
How should I take Ursoram-125 Suspension?
Who should not take Ursoram-125 Suspension?
Can I drink alcohol with Ursoram-125 Suspension?
Is Ursoram-125 Suspension safe in pregnancy?
Can I drive after taking Ursoram-125 Suspension?
Who markets Ursoram-125 Suspension?
What is the composition of Ursoram-125 Suspension?
More information
Marketed by Ramnova Healthcare Private Limited, Silvassa, India.
For dosage, pack sizes or prescribing information, refer to the current pack insert or contact Ramnova Healthcare. Catalogue information updated 2026-10-01.
- electronic medicines compendium (emc): Ursodeoxycholic acid 250 mg/5 ml oral suspension: Summary of Product Characteristics (United Kingdom, accessed 2026-10-01)
- DailyMed, U.S. National Library of Medicine: Ursodiol tablets — prescribing information (United States, accessed 2026-10-01)
