Tablets
Ursoram 300 Tablet
Ursodeoxycholic acid 300 mg tablets
Ursoram 300 is a registered product of Ramnova Healthcare Private Limited.
Ursoram 300 Tablet composition
Each uncoated tablet contains
| Ingredient | Strength |
|---|---|
| Ursodeoxycholic acidIP | 300 mg |
Also in the Ursoram range
About Ursoram 300 Tablet
URSORAM 300 tablets contain 300 mg of ursodeoxycholic acid, a bile acid. It is used to dissolve cholesterol gallstones and to treat certain long-term liver conditions, including primary biliary cholangitis. It works by improving the flow of bile and lowering the cholesterol in it, which helps gallstones dissolve and protects liver cells.
Take URSORAM after a meal with water or milk, exactly as your doctor prescribes. Treatment usually lasts several months or longer, so keep taking it even if you feel better. The most common side effect is diarrhoea or loose stools. Tell your doctor about any other medicines you take, and if you are pregnant or breastfeeding.
Therapy category: Hepatobiliary care.
Uses of Ursoram 300 Tablet
- Dissolving cholesterol gallstones in people whose gallbladder is still working
- Primary biliary cholangitis (PBC)
- Liver disease associated with cystic fibrosis
Benefits of Ursoram 300 Tablet
Cholesterol gallstones
Ursodeoxycholic acid lowers the amount of cholesterol in bile, which allows small cholesterol stones in a working gallbladder to dissolve slowly. This can take several months, so take it regularly for as long as your doctor advises. Your doctor may arrange scans to check progress.
Primary biliary cholangitis (PBC)
In PBC, the small bile ducts inside the liver are gradually damaged and bile builds up. Ursodeoxycholic acid improves bile flow and protects liver cells from harmful bile acids, which can slow the disease and improve liver test results. It is usually taken long term.
Liver disease associated with cystic fibrosis
In cystic fibrosis, thick bile can block the small bile ducts and damage the liver. Ursodeoxycholic acid helps bile flow more easily and protects liver cells. In the UK it is approved for this use in children aged 6 to 18.
Side effects of Ursoram 300 Tablet
Most side effects are mild and settle as your body adjusts. Tell your doctor if they continue or worry you.
- Diarrhoea or loose stools (the most common side effect)
- Abdominal pain
- Nausea or indigestion
- Headache
- Itching or rash
- Hair thinning
How to take Ursoram 300 Tablet
Take this medicine in the dose and for the length of time your doctor advises. Swallow the tablet whole with water or milk; do not chew or crush it. Take it with or after food.
How Ursoram 300 Tablet works
URSORAM contains ursodeoxycholic acid, a bile acid that occurs naturally in small amounts in the body. It reduces the cholesterol the liver releases into bile, which helps cholesterol gallstones dissolve. It also replaces more harmful bile acids, improves bile flow and protects liver cells from damage.
Safety advice for Ursoram 300 Tablet
- Consult your doctor
Alcohol
It is not known whether alcohol is safe with this medicine. Limit alcohol and ask your doctor.
- Use with caution
Pregnancy
Not recommended unless clearly necessary. Discuss the risks and benefits with your doctor.
- Consult your doctor
Breastfeeding
Only very small amounts are expected to pass into breast milk. Ask your doctor before use.
- Safe
Driving
Not expected to affect your ability to drive.
- Consult your doctor
Kidney
Limited information in kidney disease. Tell your doctor if you have kidney problems.
- Safe if prescribed
Liver
Used to treat certain liver conditions. Take only as prescribed, with regular liver tests.
Quick tips
- Take it after meals with water or milk, at the same time each day.
- Avoid high-fat, oily meals and limit alcohol.
- If you get diarrhoea, drink plenty of fluids and tell your doctor if it continues.
- Your doctor will check your liver tests regularly, especially in the first few months.
- Get medical help quickly for worsening jaundice, severe itching, dark urine or ongoing abdominal pain.
- Don't stop taking it without speaking to your doctor.
Warnings and interactions
Safety details must be checked against the current pack insert and advice from a qualified healthcare professional.
Warnings
- Liver function should be checked regularly during treatment
- Not recommended during pregnancy unless your doctor considers it clearly necessary. Women who could become pregnant should use non-hormonal contraception.
- Limit alcohol during treatment
Contraindications
- Acute inflammation of the gallbladder or bile ducts
- Blockage of the bile ducts
- Frequent episodes of biliary colic (severe pain in the upper abdomen)
- Calcified gallstones, or a gallbladder that does not contract properly
- An active stomach or duodenal ulcer
- In children with biliary atresia: an unsuccessful operation to restore bile flow
- Allergy to ursodeoxycholic acid or any other ingredient of the tablet
Important interactions
- Antacids containing aluminium or magnesium (such as magaldrate), cholestyramine and colestipol can reduce absorption. Take ursodeoxycholic acid at least 2 hours apart from them.
- Medicines containing oestrogen, including hormonal contraceptives, can raise cholesterol in bile and may reduce its effect on gallstones.
Frequently asked questions about Ursoram 300 Tablet
- Ursoram 300 Tablet is used for: dissolving cholesterol gallstones in people whose gallbladder is still working; primary biliary cholangitis (PBC); and liver disease associated with cystic fibrosis.
- Common side effects of Ursoram 300 Tablet include: diarrhoea or loose stools (the most common side effect); abdominal pain; nausea or indigestion; headache; itching or rash; and hair thinning. Tell your doctor if they continue or worry you.
- Take this medicine in the dose and for the length of time your doctor advises. Swallow the tablet whole with water or milk; do not chew or crush it. Take it with or after food.
- Do not take Ursoram 300 Tablet in the following cases: acute inflammation of the gallbladder or bile ducts; blockage of the bile ducts; frequent episodes of biliary colic (severe pain in the upper abdomen); calcified gallstones, or a gallbladder that does not contract properly; an active stomach or duodenal ulcer; in children with biliary atresia: an unsuccessful operation to restore bile flow; and allergy to ursodeoxycholic acid or any other ingredient of the tablet.
- It is not known whether alcohol is safe with this medicine. Limit alcohol and ask your doctor.
- Not recommended unless clearly necessary. Discuss the risks and benefits with your doctor.
- Not expected to affect your ability to drive.
- Ursoram 300 is a registered product of Ramnova Healthcare Private Limited, Silvassa, India, and is marketed by Ramnova Healthcare.
- Ursoram 300 Tablet contains ursodeoxycholic acid 300 mg (IP) in each uncoated tablet.
What is Ursoram 300 Tablet used for?
What are the side effects of Ursoram 300 Tablet?
How should I take Ursoram 300 Tablet?
Who should not take Ursoram 300 Tablet?
Can I drink alcohol with Ursoram 300 Tablet?
Is Ursoram 300 Tablet safe in pregnancy?
Can I drive after taking Ursoram 300 Tablet?
Who markets Ursoram 300 Tablet?
What is the composition of Ursoram 300 Tablet?
More information
Marketed by Ramnova Healthcare Private Limited, Silvassa, India.
For dosage, pack sizes or prescribing information, refer to the current pack insert or contact Ramnova Healthcare. Catalogue information updated 2026-10-07.
- DailyMed, U.S. National Library of Medicine: Ursodiol tablets — prescribing information (United States, accessed 2026-10-01)
- electronic medicines compendium (emc): Ursodeoxycholic acid 300 mg tablets: Summary of Product Characteristics (United Kingdom, accessed 2026-10-01)
