Capsules
Ruskitop-DSR Capsule
Enteric-coated pantoprazole sodium and sustained-release domperidone capsules
Ruskitop-DSR is a registered product of Ramnova Healthcare Private Limited.
Ruskitop-DSR Capsule composition
Product presentation
| Ingredient | Strength |
|---|---|
| Pantoprazole sodium | 40 mg |
| Domperidone | 30 mg |
About Ruskitop-DSR Capsule
RUSKITOP-DSR capsules combine enteric-coated pantoprazole 40 mg, which reduces stomach acid, with domperidone 30 mg in sustained-release form, which helps the stomach empty faster. It is used to treat acid reflux (GERD), inflammation of the food pipe caused by acid, and indigestion with bloating and nausea.
Take one capsule on an empty stomach, about 30 minutes before breakfast, exactly as your doctor prescribes. Common side effects include headache, diarrhoea and dry mouth. Domperidone can affect heart rhythm, so tell your doctor about any heart problems and every other medicine you take.
Therapy category: Gastrointestinal care.
Uses of Ruskitop-DSR Capsule
- Gastro-oesophageal reflux disease (GERD), including heartburn and acid regurgitation
- Reflux oesophagitis (inflammation of the food pipe caused by acid)
- Indigestion with bloating, fullness and nausea
Benefits of Ruskitop-DSR Capsule
Gastro-oesophageal reflux disease (GERD)
In GERD, stomach acid flows back into the food pipe, causing heartburn and irritation. Pantoprazole lowers acid production, relieving symptoms, while domperidone helps food move through the stomach faster, reducing fullness and the backflow of acid. Your doctor will decide how long you need to take it; do not stop or continue it without their advice.
Reflux oesophagitis
Repeated acid reflux can inflame and damage the lining of the food pipe. Lowering stomach acid with pantoprazole allows the lining to heal and eases pain and burning.
Indigestion with bloating and nausea
Domperidone helps the stomach empty more quickly, easing bloating, early fullness, nausea and upper abdominal discomfort, while pantoprazole reduces acid-related pain.
Side effects of Ruskitop-DSR Capsule
Most side effects are mild and settle as your body adjusts. Tell your doctor if they continue or worry you.
- Headache
- Abdominal pain, diarrhoea, constipation or bloating
- Nausea or vomiting
- Dry mouth
- Dizziness or drowsiness
- Joint pain
How to take Ruskitop-DSR Capsule
Take this medicine in the dose and for the length of time your doctor advises. Swallow the capsule whole on an empty stomach, about 30 minutes before breakfast. Do not chew, crush or open it.
How Ruskitop-DSR Capsule works
RUSKITOP-DSR combines two medicines. Pantoprazole is a proton pump inhibitor that blocks the pumps in the stomach lining that produce acid; its enteric coating protects it from stomach acid so it is absorbed further along the gut. Domperidone is a prokinetic that increases the movement of the stomach and intestines, helping food pass through faster and reducing reflux, bloating and nausea. The sustained-release form releases domperidone gradually through the day.
Safety advice for Ruskitop-DSR Capsule
- Consult your doctor
Alcohol
It is not known whether alcohol is safe with this medicine. Alcohol can also worsen acid reflux, so limit it and ask your doctor.
- Use with caution
Pregnancy
Best avoided during pregnancy unless your doctor considers it necessary.
- Unsafe
Breastfeeding
Not recommended. Domperidone passes into breast milk and may affect the baby.
- Use with caution
Driving
May cause dizziness, drowsiness or blurred vision. Do not drive until you know how it affects you.
- Use with caution
Kidney
Your doctor may need to adjust the dose or review treatment if you have severe kidney disease.
- Unsafe
Liver
Not recommended in moderate or severe liver disease. Tell your doctor if you have any liver problem.
Quick tips
- Take it about 30 minutes before breakfast, at the same time each day.
- Avoid oily or spicy food, coffee and fizzy drinks, which can worsen acidity.
- Stay upright for at least 30 minutes after taking it, and avoid lying down for 2 to 3 hours after meals.
- Get urgent medical help if you notice a fast or irregular heartbeat, fainting or fits.
- See your doctor if you have severe or persistent watery diarrhoea, or if your symptoms do not improve.
- Do not take it for longer than your doctor advises. Domperidone is used for the shortest time needed.
Warnings and interactions
Safety details must be checked against the current pack insert and advice from a qualified healthcare professional.
Warnings
- Domperidone can affect heart rhythm (QT prolongation). The risk is higher in people over 60, at higher doses and with other medicines that affect heart rhythm. It should be used at the lowest effective dose for the shortest possible time, as decided by your doctor.
- Long-term use of pantoprazole, especially beyond 3 months, may lower magnesium and vitamin B12 levels and increase the risk of bone fractures.
- It may slightly increase the risk of certain gut infections.
- Tell your doctor before starting if you have unexplained weight loss, difficulty swallowing, vomiting of blood or black stools.
Contraindications
- Heart conditions such as heart failure, or a known abnormal heart rhythm (QT prolongation)
- Moderate or severe liver disease
- Bleeding, blockage or perforation of the stomach or intestines
- A prolactin-secreting pituitary tumour (prolactinoma)
- Use with strong CYP3A4-blocking medicines such as ketoconazole, itraconazole or clarithromycin
- Allergy to pantoprazole, similar acid-reducing medicines, domperidone or any other ingredient
Important interactions
- Medicines that affect heart rhythm, such as some antiarrhythmics, antipsychotics like haloperidol, and antidepressants like citalopram or escitalopram, should not be combined with domperidone.
- The HIV medicines atazanavir and nelfinavir should not be used with pantoprazole, as it reduces their absorption.
- Pantoprazole can affect warfarin, so your INR may need checking, and can raise high-dose methotrexate levels.
- Pantoprazole reduces the absorption of ketoconazole and itraconazole, which also must not be combined with domperidone.
Frequently asked questions about Ruskitop-DSR Capsule
- Ruskitop-DSR Capsule is used for: gastro-oesophageal reflux disease (GERD), including heartburn and acid regurgitation; reflux oesophagitis (inflammation of the food pipe caused by acid); and indigestion with bloating, fullness and nausea.
- Common side effects of Ruskitop-DSR Capsule include: headache; abdominal pain, diarrhoea, constipation or bloating; nausea or vomiting; dry mouth; dizziness or drowsiness; and joint pain. Tell your doctor if they continue or worry you.
- Take this medicine in the dose and for the length of time your doctor advises. Swallow the capsule whole on an empty stomach, about 30 minutes before breakfast. Do not chew, crush or open it.
- Do not take Ruskitop-DSR Capsule in the following cases: heart conditions such as heart failure, or a known abnormal heart rhythm (QT prolongation); moderate or severe liver disease; bleeding, blockage or perforation of the stomach or intestines; a prolactin-secreting pituitary tumour (prolactinoma); use with strong CYP3A4-blocking medicines such as ketoconazole, itraconazole or clarithromycin; and allergy to pantoprazole, similar acid-reducing medicines, domperidone or any other ingredient.
- It is not known whether alcohol is safe with this medicine. Alcohol can also worsen acid reflux, so limit it and ask your doctor.
- Best avoided during pregnancy unless your doctor considers it necessary.
- May cause dizziness, drowsiness or blurred vision. Do not drive until you know how it affects you.
- Ruskitop-DSR is a registered product of Ramnova Healthcare Private Limited, Silvassa, India, and is marketed by Ramnova Healthcare.
- Ruskitop-DSR Capsule contains pantoprazole sodium 40 mg (gastro resistant) and domperidone 30 mg (prolonged release) in each capsule.
What is Ruskitop-DSR Capsule used for?
What are the side effects of Ruskitop-DSR Capsule?
How should I take Ruskitop-DSR Capsule?
Who should not take Ruskitop-DSR Capsule?
Can I drink alcohol with Ruskitop-DSR Capsule?
Is Ruskitop-DSR Capsule safe in pregnancy?
Can I drive after taking Ruskitop-DSR Capsule?
Who markets Ruskitop-DSR Capsule?
What is the composition of Ruskitop-DSR Capsule?
More information
Marketed by Ramnova Healthcare Private Limited, Silvassa, India.
For dosage, pack sizes or prescribing information, refer to the current pack insert or contact Ramnova Healthcare. Catalogue information updated 2026-10-01.
- electronic medicines compendium (emc): Pantoprazole 40 mg gastro-resistant tablets: Summary of Product Characteristics (United Kingdom, accessed 2026-10-01)
- electronic medicines compendium (emc): Domperidone 10 mg tablets: Summary of Product Characteristics (United Kingdom, accessed 2026-10-01)
