Capsules
Ruskirab-DSR Capsule
Rabeprazole 20 mg and domperidone 30 mg sustained-release capsules
Ruskirab-DSR is a registered product of Ramnova Healthcare Private Limited.
Ruskirab-DSR Capsule composition
20 mg / 30 mg SR
| Ingredient | Strength |
|---|---|
| Rabeprazole | 20 mg |
| Domperidone | 30 mg |
About Ruskirab-DSR Capsule
RUSKIRAB-DSR capsules combine rabeprazole 20 mg, which reduces stomach acid, with domperidone 30 mg in sustained-release form, which helps the stomach empty faster. It is used to treat gastro-oesophageal reflux disease (GERD), relieving heartburn, acid regurgitation, bloating and nausea.
Take one capsule on an empty stomach, about an hour before your first meal, exactly as your doctor prescribes. Common side effects include headache, diarrhoea and dry mouth. It must not be used during pregnancy or breastfeeding, and because domperidone can affect heart rhythm, tell your doctor about any heart problems and every other medicine you take.
Therapy category: Gastrointestinal care.
Uses of Ruskirab-DSR Capsule
- Gastro-oesophageal reflux disease (GERD), including heartburn and acid regurgitation
- Indigestion with bloating, fullness and nausea
Benefits of Ruskirab-DSR Capsule
Gastro-oesophageal reflux disease (GERD)
In GERD, stomach acid flows back into the food pipe, causing heartburn and irritation. Rabeprazole lowers acid production, relieving symptoms and allowing the food pipe to heal, while domperidone helps food move through the stomach faster, reducing the backflow of acid. Your doctor will decide how long you need to take it; do not stop or continue it without their advice.
Indigestion with bloating and nausea
Domperidone helps the stomach empty more quickly, easing bloating, early fullness, nausea and upper abdominal discomfort, while rabeprazole reduces acid-related pain.
Side effects of Ruskirab-DSR Capsule
Most side effects are mild and settle as your body adjusts. Tell your doctor if they continue or worry you.
- Headache
- Diarrhoea, abdominal pain or wind
- Dry mouth
- Weakness or tiredness
- Dizziness or drowsiness
- Rash
How to take Ruskirab-DSR Capsule
Take this medicine in the dose and for the length of time your doctor advises. Swallow the capsule whole on an empty stomach, about an hour before your first meal. Do not chew, crush or open it.
How Ruskirab-DSR Capsule works
RUSKIRAB-DSR combines two medicines. Rabeprazole is a proton pump inhibitor that blocks the pumps in the stomach lining that produce acid. Domperidone is a prokinetic that increases the movement of the stomach and intestines, helping food pass through faster and reducing reflux, bloating and nausea. The sustained-release form releases domperidone gradually through the day.
Safety advice for Ruskirab-DSR Capsule
- Consult your doctor
Alcohol
Alcohol can increase drowsiness and worsen acid reflux. Limit it and ask your doctor.
- Unsafe
Pregnancy
Must not be used during pregnancy.
- Unsafe
Breastfeeding
Must not be used while breastfeeding.
- Use with caution
Driving
May cause dizziness or drowsiness. Do not drive until you know how it affects you.
- Use with caution
Kidney
Your doctor may need to adjust the dose or review treatment if you have severe kidney disease.
- Unsafe
Liver
Not recommended in moderate or severe liver disease. Tell your doctor if you have any liver problem.
Quick tips
- Take it about an hour before your first meal, at the same time each day.
- Eat smaller, more frequent meals, avoid spicy or oily food, and do not lie down straight after eating.
- See your doctor if your symptoms have not improved after 2 weeks.
- Get urgent medical help if you notice a fast or irregular heartbeat, fainting or fits.
- See your doctor if you have severe or persistent watery diarrhoea or fever.
- Do not take it for longer than your doctor advises. Domperidone is used for the shortest time needed.
Warnings and interactions
Safety details must be checked against the current pack insert and advice from a qualified healthcare professional.
Warnings
- Domperidone can affect heart rhythm (QT prolongation). The risk is higher in people over 60, at higher doses and with other medicines that affect heart rhythm. It should be used at the lowest effective dose for the shortest possible time, as decided by your doctor.
- Long-term use of rabeprazole, especially beyond 3 months, may lower magnesium and vitamin B12 levels and increase the risk of bone fractures.
- It may slightly increase the risk of certain gut infections.
- Tell your doctor before starting if you have unexplained weight loss, difficulty swallowing, vomiting of blood or black stools.
Contraindications
- Pregnancy and breastfeeding
- Heart conditions such as heart failure, or a known abnormal heart rhythm (QT prolongation)
- Moderate or severe liver disease
- Bleeding, blockage or perforation of the stomach or intestines
- A prolactin-secreting pituitary tumour (prolactinoma)
- Use with strong CYP3A4-blocking medicines such as ketoconazole, itraconazole or clarithromycin
- Allergy to rabeprazole, similar acid-reducing medicines, domperidone or any other ingredient
Important interactions
- Medicines that affect heart rhythm, such as some antiarrhythmics, antipsychotics like haloperidol, and antidepressants like citalopram or escitalopram, should not be combined with domperidone.
- Rabeprazole sharply reduces the absorption of ketoconazole and itraconazole, and should not be used with the HIV medicine atazanavir.
- Rabeprazole can raise high-dose methotrexate levels, which may need monitoring.
Frequently asked questions about Ruskirab-DSR Capsule
- Ruskirab-DSR Capsule is used for: gastro-oesophageal reflux disease (GERD), including heartburn and acid regurgitation; and indigestion with bloating, fullness and nausea.
- Common side effects of Ruskirab-DSR Capsule include: headache; diarrhoea, abdominal pain or wind; dry mouth; weakness or tiredness; dizziness or drowsiness; and rash. Tell your doctor if they continue or worry you.
- Take this medicine in the dose and for the length of time your doctor advises. Swallow the capsule whole on an empty stomach, about an hour before your first meal. Do not chew, crush or open it.
- Do not take Ruskirab-DSR Capsule in the following cases: pregnancy and breastfeeding; heart conditions such as heart failure, or a known abnormal heart rhythm (QT prolongation); moderate or severe liver disease; bleeding, blockage or perforation of the stomach or intestines; a prolactin-secreting pituitary tumour (prolactinoma); use with strong CYP3A4-blocking medicines such as ketoconazole, itraconazole or clarithromycin; and allergy to rabeprazole, similar acid-reducing medicines, domperidone or any other ingredient.
- Alcohol can increase drowsiness and worsen acid reflux. Limit it and ask your doctor.
- Must not be used during pregnancy.
- May cause dizziness or drowsiness. Do not drive until you know how it affects you.
- Ruskirab-DSR is a registered product of Ramnova Healthcare Private Limited, Silvassa, India, and is marketed by Ramnova Healthcare.
- Ruskirab-DSR Capsule contains rabeprazole 20 mg and domperidone 30 mg (sustained release) in each capsule.
What is Ruskirab-DSR Capsule used for?
What are the side effects of Ruskirab-DSR Capsule?
How should I take Ruskirab-DSR Capsule?
Who should not take Ruskirab-DSR Capsule?
Can I drink alcohol with Ruskirab-DSR Capsule?
Is Ruskirab-DSR Capsule safe in pregnancy?
Can I drive after taking Ruskirab-DSR Capsule?
Who markets Ruskirab-DSR Capsule?
What is the composition of Ruskirab-DSR Capsule?
More information
Marketed by Ramnova Healthcare Private Limited, Silvassa, India.
For dosage, pack sizes or prescribing information, refer to the current pack insert or contact Ramnova Healthcare. Catalogue information updated 2026-10-01.
- electronic medicines compendium (emc): Rabeprazole sodium 20 mg gastro-resistant tablets: Summary of Product Characteristics (United Kingdom, accessed 2026-10-01)
- electronic medicines compendium (emc): Domperidone 10 mg tablets: Summary of Product Characteristics (United Kingdom, accessed 2026-10-01)
