Capsules
Esorusk-D Capsule
Esomeprazole 40 mg and domperidone 30 mg sustained-release capsules
Esorusk-D is a registered product of Ramnova Healthcare Private Limited.
Esorusk-D Capsule composition
40 mg / 30 mg SR
| Ingredient | Strength |
|---|---|
| Esomeprazole | 40 mg |
| Domperidone | 30 mg |
Also in the Esorusk range
About Esorusk-D Capsule
ESORUSK-D capsules combine esomeprazole 40 mg, which reduces stomach acid, with domperidone 30 mg in sustained-release form, which helps the stomach empty faster. It is used to treat gastro-oesophageal reflux disease (GERD), relieving heartburn, acid regurgitation, bloating and nausea.
Take one capsule on an empty stomach, 30 to 60 minutes before a meal, exactly as your doctor prescribes. Common side effects include headache, diarrhoea and dry mouth. Domperidone can affect heart rhythm, so tell your doctor about any heart problems and every other medicine you take.
Therapy category: Gastrointestinal care.
Uses of Esorusk-D Capsule
- Gastro-oesophageal reflux disease (GERD), including heartburn and acid regurgitation
Benefits of Esorusk-D Capsule
Gastro-oesophageal reflux disease (GERD)
In GERD, stomach acid flows back into the food pipe, causing heartburn and irritation. Esomeprazole lowers acid production, which relieves symptoms and allows the food pipe to heal. Domperidone helps food move through the stomach faster, reducing bloating, fullness and the backflow of acid. Your doctor will decide how long you need to take it; do not stop or continue it without their advice.
Side effects of Esorusk-D Capsule
Most side effects are mild and settle as your body adjusts. Tell your doctor if they continue or worry you.
- Headache
- Abdominal pain, diarrhoea, constipation or wind
- Nausea
- Dry mouth
- Drowsiness or dizziness
- Rash or itching
How to take Esorusk-D Capsule
Take this medicine in the dose and for the length of time your doctor advises. Swallow the capsule whole on an empty stomach, 30 to 60 minutes before a meal. Do not chew, crush or open it.
How Esorusk-D Capsule works
ESORUSK-D combines two medicines. Esomeprazole is a proton pump inhibitor that blocks the pumps in the stomach lining that produce acid. Domperidone is a prokinetic that increases the movement of the stomach and intestines, helping food pass through faster and reducing reflux, bloating and nausea. The sustained-release form releases domperidone gradually through the day.
Safety advice for Esorusk-D Capsule
- Consult your doctor
Alcohol
It is not known whether alcohol is safe with this medicine. Alcohol can also worsen acid reflux, so limit it and ask your doctor.
- Consult your doctor
Pregnancy
Use only if your doctor considers that the benefits outweigh the possible risks.
- Unsafe
Breastfeeding
Not recommended. Domperidone passes into breast milk and may affect the baby.
- Use with caution
Driving
May cause drowsiness, dizziness or blurred vision. Do not drive until you know how it affects you.
- Use with caution
Kidney
Your doctor may need to adjust the dose or review treatment if you have severe kidney disease.
- Unsafe
Liver
Not recommended in moderate or severe liver disease. Tell your doctor if you have any liver problem.
Quick tips
- Take it 30 to 60 minutes before your first meal of the day.
- Avoid large, late or spicy meals, and limit tea, coffee, chocolate and alcohol, which can worsen reflux.
- Avoid lying down for 2 to 3 hours after eating, and raise the head of your bed if symptoms are worse at night.
- Get urgent medical help if you notice a fast or irregular heartbeat, fainting or fits.
- See your doctor if you have severe or persistent watery diarrhoea, or if your symptoms do not improve.
- Do not take it for longer than your doctor advises. Domperidone is used for the shortest time needed.
Warnings and interactions
Safety details must be checked against the current pack insert and advice from a qualified healthcare professional.
Warnings
- Domperidone can affect heart rhythm (QT prolongation). The risk is higher in people over 60, at higher doses and with other medicines that affect heart rhythm. It should be used at the lowest effective dose for the shortest possible time, as decided by your doctor.
- Long-term use of esomeprazole, especially beyond 3 months, may lower magnesium and vitamin B12 levels and increase the risk of bone fractures.
- It may slightly increase the risk of certain gut infections.
- Tell your doctor before starting if you have unexplained weight loss, difficulty swallowing, vomiting of blood or black stools.
Contraindications
- Heart conditions such as heart failure, or a known abnormal heart rhythm (QT prolongation)
- Moderate or severe liver disease
- Bleeding, blockage or perforation of the stomach or intestines
- A prolactin-secreting pituitary tumour (prolactinoma)
- Use with strong CYP3A4-blocking medicines such as ketoconazole, itraconazole or clarithromycin, or with the HIV medicine nelfinavir
- Allergy to esomeprazole, similar acid-reducing medicines, domperidone or any other ingredient
Important interactions
- Medicines that affect heart rhythm, such as some antiarrhythmics, antipsychotics like haloperidol, and antidepressants like citalopram or escitalopram, should not be combined with domperidone.
- Esomeprazole can reduce the effect of clopidogrel, so the two should not be used together.
- Esomeprazole can change the levels of warfarin, methotrexate, digoxin, phenytoin and diazepam, so your doctor may need to monitor you.
- Esomeprazole reduces the absorption of some antifungals, such as ketoconazole and itraconazole, and the HIV medicine atazanavir.
Frequently asked questions about Esorusk-D Capsule
- Esorusk-D Capsule is used for: gastro-oesophageal reflux disease (GERD), including heartburn and acid regurgitation.
- Common side effects of Esorusk-D Capsule include: headache; abdominal pain, diarrhoea, constipation or wind; nausea; dry mouth; drowsiness or dizziness; and rash or itching. Tell your doctor if they continue or worry you.
- Take this medicine in the dose and for the length of time your doctor advises. Swallow the capsule whole on an empty stomach, 30 to 60 minutes before a meal. Do not chew, crush or open it.
- Do not take Esorusk-D Capsule in the following cases: heart conditions such as heart failure, or a known abnormal heart rhythm (QT prolongation); moderate or severe liver disease; bleeding, blockage or perforation of the stomach or intestines; a prolactin-secreting pituitary tumour (prolactinoma); use with strong CYP3A4-blocking medicines such as ketoconazole, itraconazole or clarithromycin, or with the HIV medicine nelfinavir; and allergy to esomeprazole, similar acid-reducing medicines, domperidone or any other ingredient.
- It is not known whether alcohol is safe with this medicine. Alcohol can also worsen acid reflux, so limit it and ask your doctor.
- Use only if your doctor considers that the benefits outweigh the possible risks.
- May cause drowsiness, dizziness or blurred vision. Do not drive until you know how it affects you.
- Esorusk-D is a registered product of Ramnova Healthcare Private Limited, Silvassa, India, and is marketed by Ramnova Healthcare.
- Esorusk-D Capsule contains esomeprazole 40 mg and domperidone 30 mg (sustained release) in each capsule.
What is Esorusk-D Capsule used for?
What are the side effects of Esorusk-D Capsule?
How should I take Esorusk-D Capsule?
Who should not take Esorusk-D Capsule?
Can I drink alcohol with Esorusk-D Capsule?
Is Esorusk-D Capsule safe in pregnancy?
Can I drive after taking Esorusk-D Capsule?
Who markets Esorusk-D Capsule?
What is the composition of Esorusk-D Capsule?
More information
Marketed by Ramnova Healthcare Private Limited, Silvassa, India.
For dosage, pack sizes or prescribing information, refer to the current pack insert or contact Ramnova Healthcare. Catalogue information updated 2026-10-01.
- electronic medicines compendium (emc): Esomeprazole 40 mg gastro-resistant capsules: Summary of Product Characteristics (United Kingdom, accessed 2026-10-01)
- electronic medicines compendium (emc): Domperidone 10 mg tablets: Summary of Product Characteristics (United Kingdom, accessed 2026-10-01)
